Plastination is a groundbreaking technique in anatomical science, offering unprecedented preservation of human tissues for education, research, and public engagement. As plastination continues to evolve, especially with increasing applications in commercial exhibitions and digital media, it is essential to establish and maintain rigorous ethical and medico-legal standards. This Statement of Position outlines the current ethical landscape, highlights challenges, and offers recommendations for the International Society of Plastination to guide responsible use of plastinated specimens and their digital reproductions. It is aligned with ethical principles established by the International Federation of Associations of Anatomists (IFAA), the American Association for Anatomy (AAA), and related international bodies.